Head to head
ShedRx vs Fridays
What each one charges a month, which pharmacy each will name, and where each will treat you — read off their own sites, not their marketing.
Both sell compounded tirzepatide — see both on our full tirzepatide list.
What each actually charges
A blank means that provider does not sell that treatment. Read each provider's cost details for the medication, commitment and additional fees behind the listed figure.
| Treatment |  |  |
|---|---|---|
| Tirzepatide | $299/mo | $389/mo |
| Semaglutide | $199/mo | $279/mo |
| Sermorelin | $199/mo | $259/mo |
| NAD+ | From $144/mo | $179/mo (quarterly prepay) |
| Glutathione | From $119/mo | Doesn't sell it |
| Pharmacy category | Not disclosed | 503A pharmacy |
ShedRx checked October 2026; Fridays checked October 2026.
Who each one suits
Good fit if you want all three term tiers on the same product page, not just the cheapest headline figure.
The catch: ShedRx's headline prices — "starting as low as $239/mo" tirzepatide, "as low as $159/mo" semaglutide — are the 12-month rate in both cases, not what you pay month to month. That figure, printed on the same product page's own tier table, is 25% higher: $299 and $199. The 12-month plan is also paid in one charge and, under its own Terms, ships 48 weeks of medication. If you cancel a prepaid plan, the months you used are recharged at the month-to-month price before anything comes back. FDA has issued no warning letter to ShedRx, "Shed," or "Shed Holdings, LLC."
Good fit if you want to know which pharmacies may fill your order.
The catch: Fridays' pricing page says "PRICE LOCKED IN FOREVER" at $99 or $198 a month. Those need a code tied to a multi-month supply, and its own Terms say a discount "will be applied to your first payment only." Without a code, a month of tirzepatide is $389. Every fee is non-refundable once charged, even if you stop treatment.
Where each one will treat you
ShedRx
All 50 states, per its own FAQ: "Shed offers telehealth services in all 50 states. Treatment availability may vary by state." No list of which treatments are limited where is published.
Fridays
Compounded medication ships to all states except Louisiana, per its help center. Its Terms say only U.S. residents are eligible and availability can vary.
Ready to start with one?
Any paid placement here is marked Partner and listed first, as a disclosed commercial position — within that group, and separately within every other row, every provider is still ranked on the criteria printed on this page, never anything else
Medical disclaimer: This content is for general educational purposes only and is not medical advice, diagnosis, or treatment. Always consult a licensed healthcare professional before starting, stopping, or changing any treatment.