Cheapest GLP-1 Without Insurance (2026): Every Compounded and Brand Cash Price, Compared

The cheapest plain monthly price we track is $69 for compounded semaglutide (SnagRx) and $109 for compounded tirzepatide (Lean Meds), across 184 and 161 sellers. The cheapest brand-name pills, Wegovy and Foundayo, start at $149 in cash.

What is the cheapest GLP-1 without insurance right now?

For a compounded GLP-1, it is $69 a month for semaglutide. That is the lowest figure on our semaglutide board that you can pay month to month with no first-month discount, no prepay and no required membership. On the tirzepatide board the same floor is $109.

Not many sellers sit near those floors. Only 3 semaglutide sellers and 3 tirzepatide sellers charge within $25 of them. The middle of the market is much higher: among sellers with a plain monthly rate, the median is $199 for semaglutide and $277 for tirzepatide.

Is compounded semaglutide or tirzepatide cheaper per month?

Semaglutide, by a wide margin. Its floor is $40 lower and its median is $78 lower. Of the 81 sellers with a plain monthly rate for both drugs, 77 charge more for tirzepatide.

Per-month price is not the only difference. The two drugs did not perform the same in their trials — see what the head-to-head trial showed. Compare like with like before you compare prices.

Why is the "$X first month" price not the real price?

Because a first-month price is paid once. Of the 589 advertised GLP-1 and peptide prices we record, only 342 (58%) are one plain monthly rate. The rest are a first month that rises, a "from" price, a per-month figure that needs a prepay, or a price plus a required fee.

That is why the lowest advertised figures sit below the floors above. The lowest on the semaglutide board is $49 — only a "from" price, from WellMedR. On tirzepatide it is $84 — only a "from" price, from RxPepsDirect. Our price transparency page sorts every advertised price by shape.

What do Wegovy, Foundayo and Zepbound cost in cash?

The manufacturers now sell direct at a fixed cash price¹²⁴:

• •Wegovy pill (oral semaglutide): $149 a month for 1.5 mg, $199 for 4 mg and $299 for 9 mg and 25 mg, through NovoCare Pharmacy¹.
• •Wegovy pen: $199 a month for the first two fills of the 0.25 mg and 0.5 mg doses for new patients, through December 31, 2026. After that it is $349, and $399 for the 7.2 mg dose¹.
• •Foundayo pill: $149 a month for 0.8 mg and 2.5 mg, $199 for 5.5 mg and $299 from 9 mg up, through LillyDirect. Foundayo is orforglipron. The 2.5 mg and 5.5 mg prices are reduced through December 31, 2026⁴.
• •Zepbound (vial or KwikPen): $299 for 2.5 mg, $399 for 5 mg and $449 for 7.5 mg to 15 mg, through LillyDirect. The $449 price requires a refill within 45 days; otherwise the higher doses cost $499 to $699².

These are FDA-approved products, so they are not the same thing as a compounded vial. If your plan covers one of them, a copay card can cost less than any cash price — see what insurance actually covers.

Is cheaper compounded GLP-1 still legal after the shortages ended?

Yes, but on narrower grounds. FDA declared the tirzepatide shortage resolved (October 2, 2024, confirmed December 19, 2024) and the semaglutide shortage resolved on February 21, 2025³. The grace periods for compounders have ended.

A state-licensed pharmacy can still compound for an individual prescription. It cannot regularly make what FDA calls "essentially a copy" of an approved drug. FDA says that rule does not apply when a prescriber documents a change that makes "a significant difference" for that patient³. Read the details for semaglutide and tirzepatide. A compounded drug is not FDA-approved and is not the same as the brand.

What else should I check besides price?

Three things, and each one can matter more than a $20 gap:

• •Who makes it. 148 of the 204 sellers on our boards do not say what kind of pharmacy makes the medication. See pharmacy transparency.
• •How you leave. Sellers differ on renewals, refunds and how to cancel. See cancellation policies.
• •What the price covers. Some prices include the visit and shipping and some do not. The semaglutide cost page and tirzepatide cost page show the advertised price next to what you actually pay each month.

If you want both drugs on one list, the weight loss injections board puts them together.