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PeptideRank

Provider review

Rx.com cost: $285/mo tirzepatide

Rx.com lists tirzepatide at $285/mo (advertised as $149/mo on a 12-mo prepay) and semaglutide at $175/mo (advertised as $99/mo on a 12-mo prepay). Prices checked October 2026.

Names its pharmacy and network; its $99 headline is a 12-month plan paid up front.

It names the dispensing pharmacy with a street address and phone number and the clinician network. Its "From $99/mo" is a 12-month plan paid as one $1,188 charge; one month is $175.

Verified October 2026

By PeptideRank Pricing Desk

Transparency scorecard

3 of 4 disclosed openly

What Rx.com discloses about itself, read from its own pages — not estimated.

Pharmacy category stated

Disclosed

Names its compounding pharmacy and states a federal regulatory category (503A/503B), sourced to its own site.

State coverage published

Disclosed

Publishes which states it actually serves.

A real price is published

Disclosed

A real dollar figure is published on its own site, not estimated.

No hidden commitment trap

Not disclosed

The advertised price requires a prepay, auto-refill, or other commitment we found and named.

This review's stake, stated plainly — some of the outbound links on this site are affiliate links; start a program through one and we may earn a commission at no extra cost to you. A commission does not change what a review says. Full disclosure here.

At a glance

Visit Rx.com

Pharmacy

503A pharmacy

Labs

Not required and not priced.

States

Published state list

On this page

How much does Rx.com cost?

Rx.com's prices, read from its own site. What you pay monthly leaves out first-month and prepay rates and includes any required membership.
Tirzepatide $149/mo on a 12-mo prepay$285/moHigher than advertised503A pharmacyOctober 2026
Semaglutide $99/mo on a 12-mo prepay$175/moHigher than advertised503A pharmacyOctober 2026

What this price covers

Medication

Included

Provider visits

Included

Shipping

Not confirmed

Lab work

Not required

Coaching

Not confirmed

The catch — The advertised figure is a 12-month commitment charged as one payment. $99 a month means $1,188 today, for medication at doses a clinician has not prescribed yet, on a product whose sales are final once it ships.

See plans at Rx.com

Prices read from Rx.com's own site

What they advertise

"From $99/mo" in the site banner and on every product page, with "*12-month plan, $1,188 one payment" beneath it. Tirzepatide is advertised the same way, "From $149/month".

What you actually pay

$175 a month for compounded semaglutide and $285 for compounded tirzepatide, buying one month at a time. Each product page prints all four plan lengths: semaglutide $175 monthly, $495 for three months, $875 for six and $1,188 for twelve; tirzepatide $285, $795, $1,550 and $1,788.

Money you will meet later

  • Once a package is handed to the carrier, all sales are final; prescription medication cannot be returned once dispensed.
  • The online visit asks for a photo ID, and some states add a short video visit.

The bottom line

Rx Platform LLC sells compounded semaglutide at $175 a month and compounded tirzepatide at $285, with the provider visit, injection supplies and shipping in the price and the same rate at every dose. Its disclosure is unusually complete: Manifest Pharmacy is named with an address and a phone number, the MD Integrations clinician network is named, and its Terms cite Section 503A directly. The catch is the headline. The "From $99/mo" on every page is a 12-month plan paid in one $1,188 charge, and medication cannot be returned once it ships.

Rx.com appears on our tirzepatide provider ranking, our semaglutide provider ranking and our combined weight loss injections ranking.

Who is Rx.com for, and who is it not for?

A good fit if

  • You want to know which pharmacy fills it: Manifest Pharmacy in Greer, South Carolina, with a street address and phone number.
  • You want one price at every dose, with the visit, syringes and shipping in it.
  • You want no automatic billing: its product pages say plans do not renew and nothing ships or is charged until you confirm a refill.

Look elsewhere if

  • You are shopping on the advertised price. $99 buys twelve months at once, in a single $1,188 charge; one month at a time is $175.
  • You want to try it for a month or two before paying for a year: the savings only arrive with a large up-front payment.
  • You live in Alaska, the one state it does not serve.

What Rx.com offers

Tap any compound to read our plain-English guide — what the evidence shows, how it is dosed, and what it costs elsewhere.

Who fills your prescription

503A pharmacy

Rx.com names pharmacy partners and states a compounding category. Confirm which partner will fill your prescription.

  • Manifest Pharmacy
What its own site says

Named, addressed and categorized. Its Terms state that weight-loss prescriptions are dispensed by Manifest Pharmacy, 1018 S. Batesville Road, Greer, South Carolina, with a phone number and staffed hours; that compounded medications are prepared by pharmacies complying with Section 503A of the Federal Food, Drug, and Cosmetic Act; and that clinical care comes from the MD Integrations provider network. It says plainly that it is a marketplace, does not dispense medication, does not provide medical services, and that payment does not guarantee a prescription.

What's the difference between 503A and 503B?

A 503A pharmacy compounds for one named patient; a 503B outsourcing facility manufactures in batches under CGMP. Neither is a quality guarantee on its own — a named facility is simply a fact you can check, and an unnamed “partner pharmacy network” is not. Compounded peptides are not FDA-approved.

Where you can get it

Published state list

Forty-nine: "We currently serve 49 states (all except Alaska)." Some states require a short video visit, handled during intake.

The honest cons

The part they would rather you skipped

Rx.com's headline is a year's commitment. "From $99/mo" sits in its banner and on every product page, and the asterisk under it reads "12-month plan, $1,188 one payment". The month-to-month rate is $175 for semaglutide and $285 for tirzepatide; the page prints both, but the $99 is the number it repeats. That $1,188 is due up front, before a clinician has set a dose, on medication that cannot be returned once it ships. Smaller things do not line up either: its product pages promise cold-packed shipping while its refund policy says it does not ship refrigerated products, and that policy speaks of canceling "your subscription" while the product pages say plans never renew.

  • The advertised $99 and $149 are 12-month plans charged as single payments of $1,188 and $1,788.
  • Medication sales are final once the package reaches the carrier.
  • Its product pages say cold-packed shipping; its refund policy says it does not ship refrigerated products.
  • Not available in Alaska.
  • Its search menu still shows older prices ($146 semaglutide, $259 tirzepatide).
  • The same company runs a prescription discount-card business alongside the telehealth one, with an Amazon affiliate disclosure in the footer.

How it compares

Read this before you buy

A provider comparison is half the decision. The other half is whether the compound does anything for you at all. The evidence below is where that gets settled.

Ready to get started?

Prices and plans in this category change often — check Rx.com's current pricing before you decide. Ours was read from their own site.

See Rx.com pricing

Facts on this page reflect Rx.com's own public disclosures when we last checked them. Prices and terms change without notice — confirm on Rx.com's site before you buy. Provider names and logos on this page identify the company under review; their use does not imply endorsement, sponsorship or affiliation. This page is informational and not medical advice; compounded peptides are not FDA-approved. See our disclosure and editorial policy.