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PeptideRank

Provider review

Sesame Care review

A flat, medication-included semaglutide plan — but tirzepatide is separate and unpriced.

Sesame Care's "Success by Sesame" compounded-semaglutide subscription is a real, direct, price-inclusive product with a stated 503B pharmacy category. But the identical company's compounded-tirzepatide pathway is structured completely differently — a "book a provider of your choice" marketplace where medication cost is not included — a real, verified split within one brand, not an assumption.

Verified August 2026Partner

Reviewed by Marcus Webb

Transparency scorecard

4 of 4 disclosed openly

What Sesame Care discloses about itself, read from its own pages — not estimated.

Pharmacy named & regulated

Disclosed

Names its compounding pharmacy and states a federal regulatory category (503A/503B), sourced to its own site.

State coverage published

Disclosed

Publishes which states it actually serves.

A real price is published

Disclosed

A real dollar figure is published on its own site, not estimated.

No hidden commitment trap

Disclosed

The advertised price is the ongoing price — no prepay or auto-refill required to unlock it.

This review's stake, stated plainlysome of the outbound links on this site are affiliate links; start a program through one and we may earn a commission at no extra cost to you. Straight about the rest, too: the write-ups say what each provider is actually worth, and a commission does not change a word of them. Full disclosure here.

At a glance

Visit Sesame Care

Real monthly cost

$249/month is the standing, disclosed renewal rate

Pharmacy

503B

Labs

"Order for lab(s) relevant to weight loss…

States

All-50

On this page

What it actually costs

High confidence

What they advertise

"Weight loss for $249/mo., medication included" — Sesame's own compounded-semaglutide landing page headline.

What you actually pay, month to month

$249/month is the standing, disclosed renewal rate. A first-month promotional rate may apply at times (e.g., a Cyber Monday $149 first-month offer seen on the live site), but the same disclosure states plainly it "will renew at $249/month thereafter."

Money you will meet later

  • Lab costs relevant to weight-loss treatment are itemized as included, except in NJ, NY, and RI, where they're excluded per Sesame's own page.

Price read from https://www.sesamecare.com/service/online-weight-loss-program.

The bottom line

Sesame Care (sesamecare.com, legal entity Sesame, Inc.) is a large, well-known cash-pay telehealth marketplace. Its "Success by Sesame" plan is a genuine flat $249/month subscription with compounded semaglutide included, dispensed exclusively by 503B compounding pharmacies per its own unhedged claim. Its compounded tirzepatide, by contrast, is sold through a referral marketplace where a reader books an independent provider and pays for medication separately — different enough in structure that this review ranks Sesame Care on the semaglutide board only.

Sesame Care appears on our semaglutide provider ranking and our combined weight loss injections ranking. Nothing on this page is a performance claim.

Who it is for, and who it is not

A good fit if

  • You want a large, established telehealth brand with a real Trustpilot track record (4.5 stars, cited on its own site) rather than a newer, smaller company.
  • A flat, medication-included monthly price for compounded semaglutide, with no dose-tier math to work through, is what you're after.
  • You're comfortable with Sesame's own cancellation caveat: using provider messaging after your initial visit forfeits refund eligibility.

Look elsewhere if

  • You're looking for the SAME kind of direct, price-inclusive product for compounded tirzepatide — Sesame's tirzepatide pathway is a different, referral-marketplace model with no company-set price.
  • You want a specific, named compounding pharmacy rather than a stated regulatory category (503B) with no company named.
  • You plan to use provider messaging or other service features before deciding whether to keep the subscription — doing so forfeits refund eligibility per Sesame's own Refund Policy.

What is included

The cheapest headline number in this category is often the one with the least attached to it. Here is what Sesame Care bundles in, and what it does not.

Clinician consult

Included

— "Initial video consult" is itemized directly in Sesame's own included-items list for the compounded-semaglutide plan.

Bloodwork / labs

"Order for lab(s) relevant to weight loss treatment/diagnoses"…

and their cost are itemized as included, with NJ/NY/RI excluded per its own page.

Follow-ups and dose changes

"Ongoing care for weight loss and management" is itemized…

directly in its own included-items list; no specific cadence is stated.

Human support

"Unlimited messaging with provider" is marketed, but no…

dietitian, nurse, or named coaching program is stated.

Injection supplies

Not stated.

Shipping

"Medication delivery to your doorstep + free shipping" is…

stated directly in its own benefit list.

Who fills it, and who's watching

The pharmacy

503B. Sesame's own compounded-semaglutide landing page states directly, "The compounded semaglutide available for prescribing on Sesame is prepared exclusively by 503B compounding pharmacies that are FDA-registered," repeated in a separate bullet, "Medication supplied from a registered 503B pharmacy." No specific pharmacy is named, only the regulatory category.

Oversight

Included — "Initial video consult" is itemized directly in Sesame's own included-items list for the compounded-semaglutide plan. "Ongoing care for weight loss and management" is itemized directly in its own included-items list; no specific cadence is stated.

Compounded peptides are not FDA-approved products, and a 503A pharmacy compounds for a named patient while a 503B outsourcing facility manufactures in batches under CGMP. Neither is a quality guarantee on its own — a named facility is simply a fact you can check, and an unnamed “partner pharmacy network” is not.

Where you can get it

All-50. Sesame's own compounded-semaglutide landing page states "Available in all 50 states" directly beneath the price, with no contradicting figure found on the same page.

The honest cons

The part they would rather you skipped

Sesame's own Refund Policy, read in full, narrows the refund window sharply for anyone who actually uses the service before deciding to cancel: "Please note that we cannot offer full or partial refunds for our weight loss program if, after your initial visit, you have utilized other features of the service, such as provider messaging." A reader who messages their provider with a follow-up question — the exact behavior the plan's own "unlimited messaging" benefit encourages — forfeits refund eligibility. Separately, this same company's compounded-tirzepatide product is a materially different offering from its compounded-semaglutide one: the tirzepatide flow is a book-a-provider marketplace ("Book with a top-rated provider of your choice through Sesame's weight loss program") where the page states plainly "Cost of medication not included" and a prescription may be picked up "at a pharmacy near you" — a reader assuming Sesame's semaglutide deal (flat price, medication included, nationwide) also describes its tirzepatide offering would be wrong. No FDA warning letter could be independently confirmed for "Sesame Care" or "Sesame, Inc." this round; noted honestly rather than presented as a clean check.

  • Refund eligibility for the weight-loss program ends the moment a reader uses provider messaging or other service features after the initial visit, per its own Refund Policy.
  • The identical brand's compounded-tirzepatide product is a referral marketplace with no company-set price — a materially different structure from its compounded-semaglutide subscription, easy to assume is the same and isn't.
  • Only a regulatory category (503B) is stated for its pharmacy network; no specific pharmacy is named anywhere on the site.

None of this is unique to Sesame Care — the whole category shares it.

How it compares

Read this before you buy

A provider comparison is half the decision. The other half is whether the compound does anything for you at all — and whether it is allowed where you compete. Growth-hormone secretagogues are banned in tested sport, year-round, and a prescription does not change that.

Facts on this page reflect Sesame Care's own public disclosures when we last checked them, in August 2026. Prices and terms change without notice — confirm on Sesame Care's site before you buy. Provider names and logos on this page identify the company under review; their use does not imply endorsement, sponsorship or affiliation. This page is informational and not medical advice; compounded peptides are not FDA-approved, and growth-hormone secretagogues are banned in tested sport year-round. See our disclosure and editorial policy.

Sesame Care

$249/month is the standing, disclosed…

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