Ranked above it
Care Bare Rx
Tells you exactly what you're buying — but $199 is a starting point, not a rate.
#1 on our semaglutide provider ranking, above Sesame Care at #2.
Read the Care Bare Rx review →
Provider review
Sesame Care cost: $249/mo semaglutide
A flat, medication-included semaglutide plan — tirzepatide works nothing like it.
"Success by Sesame" is a real, direct, price-inclusive compounded-semaglutide subscription with a stated 503B pharmacy category. The same company's compounded tirzepatide is built completely differently: you book a provider of your choice and pay for the medication separately. Two products, one brand, and almost nothing in common.
Verified August 2026
Reviewed by Marcus Webb
Transparency scorecard
4 of 4 disclosed openly
What Sesame Care discloses about itself, read from its own pages — not estimated.
Pharmacy named & regulated
Disclosed
Names its compounding pharmacy and states a federal regulatory category (503A/503B), sourced to its own site.
State coverage published
Disclosed
Publishes which states it actually serves.
A real price is published
Disclosed
A real dollar figure is published on its own site, not estimated.
No hidden commitment trap
Disclosed
The advertised price is the ongoing price — no prepay or auto-refill required to unlock it.
This review's stake, stated plainly — some of the outbound links on this site are affiliate links; start a program through one and we may earn a commission at no extra cost to you. Straight about the rest, too: the write-ups say what each provider is actually worth, and a commission does not change a word of them. Full disclosure here.
At a glance
Visit Sesame CarePharmacy
503B facility
Labs
"Order for lab(s) relevant to weight loss…
States
All 50 states
On this page
What it actually costs
$249/moSemaglutide, per month
What this price covers
Medication
Included
Provider visits
Included
Shipping
Not confirmed
Lab work
Not confirmed
Coaching
Not confirmed
Prices read from Sesame Care's own site · August 2026
What they advertise
"Weight loss for $249/mo., medication included" — Sesame's own compounded-semaglutide landing page headline.
What you actually pay
$249 a month is the standing renewal rate, disclosed as such. A promotional first month turns up at times — a Cyber Monday $149 offer was live on the site — but the same disclosure says plainly it "will renew at $249/month thereafter."
Money you will meet later
- Lab costs relevant to weight-loss treatment are included, except in NJ, NY and RI, where Sesame's own page excludes them.
The bottom line
Sesame Care (sesamecare.com, legally Sesame, Inc.) is a large, well-known cash-pay telehealth marketplace. Its "Success by Sesame" plan is a genuine flat $249 a month with compounded semaglutide included, dispensed exclusively by 503B compounding pharmacies — its own claim, plain. Its compounded tirzepatide is a different product entirely: a referral marketplace where you book an independent provider and pay for the medication yourself. Different enough that Sesame Care is ranked for semaglutide only.
Sesame Care appears on our semaglutide provider ranking and our combined weight loss injections ranking. Nothing on this page is a performance claim.
Who it is for, and who it is not
A good fit if
- You want a large, established brand with a real Trustpilot record (4.5 stars, cited on its own site) over a newer, smaller company.
- You want a flat, medication-included monthly price for compounded semaglutide, with no dose-tier math to work through.
- You can live with Sesame's refund caveat: message your provider after the first visit and you give up the refund.
Look elsewhere if
- You want the same direct, price-inclusive deal for compounded tirzepatide — that one is a referral marketplace with no company-set price.
- You want a named compounding pharmacy, not a category — Sesame states 503B and names nobody.
- You plan to use provider messaging before deciding whether to keep the subscription — doing so ends your refund eligibility, per Sesame's own Refund Policy.
What Sesame Care offers
Tap any compound to read our plain-English guide — what the evidence shows, how it is dosed, and what it costs elsewhere.
Who fills your prescription
503B facility
Sesame Care names the pharmacy that fills your prescription.
What its own site says
503B — the category, and only the category. Sesame's compounded-semaglutide page says, "The compounded semaglutide available for prescribing on Sesame is prepared exclusively by 503B compounding pharmacies that are FDA-registered," and repeats it in a bullet: "Medication supplied from a registered 503B pharmacy." No pharmacy is ever named.
What's the difference between 503A and 503B?
A 503A pharmacy compounds for one named patient; a 503B outsourcing facility manufactures in batches under CGMP. Neither is a quality guarantee on its own — a named facility is simply a fact you can check, and an unnamed “partner pharmacy network” is not. Compounded peptides are not FDA-approved.
Where you can get it
All 50 states
All 50. "Available in all 50 states" sits directly beneath the price on the compounded-semaglutide page, with nothing on that page contradicting it.
The honest cons
The part they would rather you skipped
Read Sesame's Refund Policy all the way through and the refund window narrows sharply for anyone who actually uses the service first: "Please note that we cannot offer full or partial refunds for our weight loss program if, after your initial visit, you have utilized other features of the service, such as provider messaging." Message your provider with a follow-up question — the exact thing the plan's "unlimited messaging" benefit invites — and the refund is gone. The other thing worth knowing: this same company's compounded tirzepatide is a different offering altogether. That flow is a book-a-provider marketplace ("Book with a top-rated provider of your choice through Sesame's weight loss program") where the page says "Cost of medication not included" and the prescription may be picked up "at a pharmacy near you." Anyone assuming the semaglutide deal — flat price, medication included, nationwide — describes the tirzepatide one would be wrong. FDA has issued no warning letter to Sesame Care. or "Sesame, Inc." That is an absence, not a clearance.
- Refund eligibility ends the moment you use provider messaging or another feature after the initial visit, per its own Refund Policy.
- The same brand's compounded tirzepatide is a referral marketplace with no company-set price — easy to assume it matches the semaglutide subscription, and it doesn't.
- Only a category (503B) is stated for its pharmacy network; no pharmacy is named anywhere on the site.
None of this is unique to Sesame Care — the whole category shares it.
How it compares
The providers we rank on our semaglutide provider ranking — the most specific board Sesame Care sits on — in the order that board ranks them. It sells into other categories too; see the boards listed above under the bottom line.
- Care Bare RxTells you exactly what you're buying — but $199 is a starting point, not a rate.
- SnagRx"Locked-In... for Life" pricing sits beside a countdown claiming otherwise.
- Sprout HealthNames both pharmacies and a real 44-state list — but every price is a starting floor.
- HealthRXStructured, disclosed pricing — but no legal entity is named anywhere on the site.
- Breeze MedsNames the exact compound in its nav — then hides the price behind a quiz.
- SkinnyRxInjectable and oral tirzepatide — but the advertised price is a floor, not what you pay.
- TrimiNames its two pharmacies outright — then headlines a price that needs a year upfront.
- Enhance MDHonest pricing and a real 503A claim — but it isn't in all 50 states, whatever it says.
175 more providers rank on our semaglutide provider ranking — see the full ranking. Every provider we review →
Read this before you buy
A provider comparison is half the decision. The other half is whether the compound does anything for you at all. The evidence below is where that gets settled.
Ready to get started?
Prices and plans in this category change often — check Sesame Care's current pricing before you decide. Ours was read from their own site in August 2026.
Facts on this page reflect Sesame Care's own public disclosures when we last checked them, in August 2026. Prices and terms change without notice — confirm on Sesame Care's site before you buy. Provider names and logos on this page identify the company under review; their use does not imply endorsement, sponsorship or affiliation. This page is informational and not medical advice; compounded peptides are not FDA-approved. See our disclosure and editorial policy.
Sesame Care
$249/mo · Semaglutide